Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

NARecruitingINTERVENTIONAL
Enrollment

1,350

Participants

Timeline

Start Date

March 10, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Opioid OverdoseOpioid UseOpioid Use DisorderOpioids
Interventions
BEHAVIORAL

EHR-Embedded Elevated-Risk Flag

Clinicians seeing patients at elevated predicted risk will see a flag on the EHR 'storyboard' during in person or telephone encounters indicating the patient is at elevated predicted risk of opioid overdose. The clinician will have the option of including this information into their decision-making process when providing care. There will be no best practice alerts/behavioral nudges in this arm.

BEHAVIORAL

EHR-Embedded Elevated-Risk Flag with Behavioral Nudges

"Clinicians seeing patients at elevated predicted risk for opioid overdose will see a flag on the EHR storyboard indicating that the patient is at elevated predicted risk.~Clinicians will also receive up to 4 best practice alerts/behavioral nudges during an in-person or telephone primary care encounter with elevated risk patients when certain requirements are met: 1) if the patient does not have an active naloxone prescription on their medication list, the clinicians will receive an active choice alert during any medication ordering to encourage naloxone prescription; 2) if the patient's opioid dosage is \>50 MME, OR they are ordered a new opioid prescription, OR they have an overlapping opioid and benzodiazepine prescription order, the clinicians will receive an accountable justification alert when the relevant order is entered."

BEHAVIORAL

Usual Care

Patients in the practices randomized to the Usual Care arm will receive standard care practice without change.

Trial Locations (1)

15213

RECRUITING

University of Pittsburgh, Pittsburgh

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

University of Pittsburgh

OTHER