The OSIRIS ECPR Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

686

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

June 30, 2029

Study Completion Date

June 30, 2030

Conditions
Cardiac ArrestVentricular FibrillationOut-Of-Hospital Cardiac ArrestSudden Cardiac ArrestExtracorporeal Cardiopulmonary ResuscitationExtracorporeal Membrane Oxygenation
Interventions
PROCEDURE

Extracorporeal cardiopulmonary resuscitation based approach

ECPR-based approach is defined as ACLS per current guidelines with aim to proceed to in-hospital or out-of-hospital V-A ECMO if ROSC is not achieved before the cannulation.

PROCEDURE

Conventional cardiopulmonary resuscitation

CCPR is defined as conventional ACLS per current guidelines without MCS use until sustained ROSC is achieved or the patient pronounced dead.

All Listed Sponsors
collaborator

Karolinska Institutet

OTHER

collaborator

Heinrich-Heine University, Duesseldorf

OTHER

collaborator

University Hospital Freiburg

OTHER

collaborator

University Medical Centre Ljubljana

OTHER

collaborator

Medical University of Vienna

OTHER

collaborator

Hospital Vall d'Hebron

OTHER

collaborator

Heart Center Leipzig - University Hospital

OTHER

collaborator

Aarhus University Hospital

OTHER

collaborator

Royal Brompton & Harefield NHS Foundation Trust

OTHER

collaborator

Region Hovedstadens Apotek

OTHER_GOV

collaborator

Ludwig-Maximilians - University of Munich

OTHER

collaborator

European Clinical Research Infrastructure Network

OTHER

collaborator

Masaryk University

OTHER

collaborator

Insel Gruppe AG, University Hospital Bern

OTHER

collaborator

University Hospital, Zürich

OTHER

collaborator

University of London

OTHER

collaborator

Uniwersytet Wrocławski

UNKNOWN

lead

General University Hospital, Prague

OTHER