Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

March 27, 2025

Primary Completion Date

March 31, 2030

Study Completion Date

September 30, 2030

Conditions
Acute LeukemiaAcute Lymphoblastic Lymphoma
Interventions
RADIATION

200 cGy or 400 cGy total body irradiation (TBI)

Either 200 or 400cGy will be given as part of reduced-intensity conditioning prior to consolidative allogeneic bone marrow transplant (alloBMT)

Trial Locations (1)

21287

RECRUITING

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

All Listed Sponsors
lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER