ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer

NARecruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

May 12, 2025

Primary Completion Date

July 31, 2029

Study Completion Date

July 31, 2029

Conditions
Pancreatic Cancer
Interventions
PROCEDURE

Total pancreatectomy (TP)

The investigators perform TP in patients who undergo surgical resection of a malignant tumor in the pancreatic head.

PROCEDURE

Partial pancreaticoduodenectomy (PD)

The investigators perform partial PD with anastomosis of the pancreas in patients who undergo surgical resection of a malignant tumor in the pancreatic head. This is the current standard procedure.

Trial Locations (7)

1205

RECRUITING

Department of Visceral Surgery, University Hospital Geneva, Geneva

3010

RECRUITING

Inselspital, Bern University Hospital, Bern

4031

NOT_YET_RECRUITING

Department of Visceral Surgery, University Hospital Basel, Basel

5404

RECRUITING

Department of Surgery, Kantonsspital Baden, Baden

8063

NOT_YET_RECRUITING

Department of Surgery, Stadtspital Triemli Zürich, Zurich

8091

RECRUITING

Department of Surgery and Transplantation, University Hospital Zürich, Zurich

9000

RECRUITING

Department of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, Sankt Gallen

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER