Determining the Fingerprint of Endotoxin Tolerance

NACompletedINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

May 27, 2019

Primary Completion Date

February 20, 2020

Study Completion Date

August 20, 2020

Conditions
EndotoxemiaSepsisSystemic InflammationImmunosuppresion
Interventions
OTHER

Endotoxin (E. coli O:113, Reference Endotoxin)

Intravenous administration of 1 ng/kg (total body weight) endotoxin (Lot no. 94332B1; List Biological Laboratories, Campbell, USA). This is a non-investigational product. Endotoxin is used as challenge agent to achieve a controlled inflammatory state.

Trial Locations (1)

6500HB

Intensive Care Medicine Deparmtent, Nijmegen

All Listed Sponsors
lead

Radboud University Medical Center

OTHER

NCT06801873 - Determining the Fingerprint of Endotoxin Tolerance | Biotech Hunter | Biotech Hunter