Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery

RecruitingOBSERVATIONAL
Enrollment

70

Participants

Timeline

Start Date

March 28, 2025

Primary Completion Date

March 28, 2027

Study Completion Date

August 6, 2027

Conditions
Coronary Artery BypassGraft FailureCoronary Artery Bypass GraftCoronary Artery Bypass Graft Surgery (CABG)
Interventions
RADIATION

Hybrid [18F]-GP1, [68Ga]-DOTATATE, [68Ga]-FAPI total-body positron emission tomography and coronary computed tomography coronary angiography

Patients undergo hybrid \[18F\]-GP1, \[68Ga\]-FAPI and \[68Ga\]-DOTATATE total body PET-CT imaging (Biograph Vision Quadra, Siemens) and contrast-enhanced electrocardiogram gated CT coronary angiogram (CTCA), within 28 days (+/- 28 days) of their CABG surgery and again at 12 month follow-up.

RADIATION

Hybrid [18F]-GP1, [68Ga]-DOTATATE, [68Ga]-FAPI total-body positron emission tomography and coronary computed tomography coronary angiography

Patients undergo hybrid \[18F\]-GP1, \[68Ga\]-FAPI and \[68Ga\]-DOTATATE total body PET-CT imaging (Biograph Vision Quadra, Siemens) and contrast-enhanced electrocardiogram gated CT coronary angiogram (CTCA), prior to their clinical invasive coronary angiography.

Trial Locations (1)

EH16 4SA

RECRUITING

Royal Infirmary of Edinburgh, Edinburgh

All Listed Sponsors
collaborator

NHS Lothian

OTHER_GOV

lead

University of Edinburgh

OTHER