NCT06798038View on ClinicalTrials.gov

Comparison of the Efficacy of Chemical Genicular Nerve Neurolysis Using Alcohol or Phenol Versus Radiofrequency Ablation Under Ultrasound Guidance for Pain Management in Patients With Knee Osteoarthritis

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

March 1, 2027

Conditions
Assessment of Pain Intensity Using 10-point Numerical Rating Scale (NRS-10)(9)Immediately After Intervention , 1 Week,1month,3 Months,6months and One YearAssessment of Knee Function Using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)Knee Osteoarthritis
Interventions
DEVICE

radiofrequency ablation

35 Patients will be undergo for radiofrequency ablation which will be applied to each genicular nerve.

DRUG

phenol neurolysis

35 Patients will be administered with 2.0 ml of 6% phenol solution prepared from crystallized phenol per genicular nerve

DRUG

alcohol neurolysis

35 Patients will be administered with 1.0ml of 70% alcohol per genicular nerve

All Listed Sponsors
lead

Tanta University

OTHER