Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions.

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 17, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

December 31, 2026

Conditions
GlioblastomaGliomaAstrocytoma
Interventions
DIAGNOSTIC_TEST

Functional MRI

"11 minutes of Functional MRI alternating breathing Air-Room and gaz mix (5%CO2 21%O2 74%N2).~All procedure are acquired simultaneously on a single acquisition on the PET/MRI camera in the institution."

DIAGNOSTIC_TEST

FDG-PET

"Some patients who did not benefit from a FDG-PET in their clinical evaluation or more than 1 month before the inclusion in the present study will be ask to also undergo a brain FDG-PET , the dose is set at 2 Mega becquerel per Kg.~All procedure are acquired simultaneously on a single acquisition on the PET/MRI camera in the institution."

DIAGNOSTIC_TEST

Structural MRI

"Patient will benefit Different anatomical sequence of acquisition listed here : T1 , T1 with contrast agent (gadovist) , T2 flair , T2 and DSC (Dynamic susceptibility contrast) , and Time Of Flight .~All procedure are acquired simultaneously on a single acquisition on the PET/MRI camera in the institution."

Trial Locations (1)

1060

RECRUITING

HUB-Erasme Hospital, Brussels

All Listed Sponsors
lead

Erasme University Hospital

OTHER