Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy

NARecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

February 10, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

October 31, 2027

Conditions
Adrenomyeloneuropathy Without Cerebral Involvement
Interventions
PROCEDURE

Spinal cord stimulation

Upon completion of the initial assessments, a lumbar spinal cord nerve stimulator and pulse generator will be implanted. Following surgery, based on the patient's recovery status, the patient will be transferred to the respective center for rehabilitation within one to two weeks. Afterward, electrical stimulation therapy will be initiated. Stimulation should be applied at least three days per week. Each day, the total stimulation time should be between 4 and 8 hours. Stimulation Modes: Continuous Stimulation: For example, if 6 hours of stimulation are prescribed, the stimulator will run uninterrupted for 6 hours. Intermittent Stimulation: For instance, a cycle of 40 seconds on and 20 seconds off. If a total of 6 hours of active stimulation is needed, the stimulator must remain on for 9 hours in total to accommodate rest intervals.The ranges for each parameter are as follows:Stimulation Frequency: 2 Hz - 2000 Hz, Pulse Width: 20 μs - 1000 μs, Stimulation Amplitude:Voltage: 0 V - 10 v

Trial Locations (4)

100070

ACTIVE_NOT_RECRUITING

Beijing TianTan Hospital, Beijing

400020

RECRUITING

The 958 Hospital of Chinese People's Liberation Army, The Jiangbei Campus of Southwest Hospital, The First Affiliated Hospital of Army Medical University, Chongqing

400038

RECRUITING

the Southwest hospital, Chongqing

448000

ACTIVE_NOT_RECRUITING

Jingmen No.1 People's Hospital, Jingmen

All Listed Sponsors
collaborator

Beijing Tiantan Hospital

OTHER

collaborator

Jingmen No.1 People's Hospital

OTHER

collaborator

The 958th Hospital of the Chinese People's Liberation Army

UNKNOWN

lead

Third Military Medical University

OTHER