Exploring the Impact of Nephropathy Formula No. 1 on Chronic Kidney Disease Patients

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

December 1, 2027

Study Completion Date

December 31, 2027

Conditions
Renal Insufficiency, Chronic
Interventions
DRUG

Nephropathy Formula No. 1

On the basis of integrated treatment for chronic kidney disease (the specific plan is the same as the control group), Nephropathy Formula No. 1 is given orally. The composition and decoction method of the formula are as follows: Bupleurum, Paeonia lactiflora Pall. , Scutellaria baicalensis Georgi , Pinellia ternata (Thunb.) Breit. , Smilax glabra Roxb. , Oldenlandia diffusa (Willd.) Roxb. , Tussilago farfara L. , Poria cocos (Schw.) Wolf , decocted into 300ml, one dose per day, taken warm in two divided doses for 12 weeks.

DRUG

integrated basic treatment for chronic kidney disease

"The integrated basic treatment for CKD includes the following:~Dietary Nutrition: α-Keto acid tablets (2.6 g tid) may be used. Blood Pressure Control: Antihypertensive drugs such as amlodipine tablets (5 mg qd), nifedipine tablets (30 mg qd), or losartan tablets (100 mg qd) can be selected. β-blockers or α-blockers may be used in combination if necessary.~Blood Sugar Control: Medications such as repaglinide tablets (1.0 mg qd) or gliclazide modified-release tablets (30 mg qd) can be used.~Lipid Control: Medications such as atorvastatin calcium tablets (20 mg qd) or fenofibrate capsules (0.2 g qd) can be used.~Anemia Treatment: Recombinant human erythropoietin (10000 u qw) can be administered via subcutaneous injection.~Regulation of Water, Electrolyte, and Acid-Base Metabolic Balance."

Trial Locations (3)

310053

The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou

Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Hangzhou

325000

Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou

All Listed Sponsors
lead

Liu Zhanghong

OTHER