NCT06794034View on ClinicalTrials.gov

Efficacy of taVNS Versus Sham Stimulation in Reduing Depressive Symptoms in Patients With Epilepsy: a Multi-center, Double-blinded, Randomized, 20-week, Parallel-arm, Superiority Study

NAActive, not recruitingINTERVENTIONAL
Enrollment

158

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

December 30, 2025

Study Completion Date

December 31, 2025

Conditions
Depressive Symptoms in Patients With Epilepsy
Interventions
DEVICE

Intervention

taVNS 25Hz+routine treatment, three times daily, 30 mins

DEVICE

Sham Comparator

taVNS 1Hz+routine treatment, three times daily, 30 mins

Trial Locations (5)

310009

The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou

314000

The First People's Hospital of Jiaxing, Jiaxing

315040

Ningbo Medical Center Li Huili Hospital, Ningbo

321000

Jinhua Second Hospital, Jinhua

322000

The Fourth Affiliated Hospital, School of Medicine, Zhejiang University, Yiwu

All Listed Sponsors
collaborator

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

OTHER

collaborator

Ningbo Medical Center Lihuili Hospital

OTHER_GOV

collaborator

First Affiliated Hospital of Zhejiang University

OTHER

collaborator

Jinhua Second Hospital

UNKNOWN

lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER