Effects of Nicorandil on Microvascular Dysfunction in Patients With STEMI Undergoing Primary PCI

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
STEMI - ST-segment Elevation Myocardial Infarction
Interventions
DRUG

nicorandil

In the nicorandil group, intracoronary nicorandil 3mg dissolved in 3ml saline was given within 30 seconds at two time points, one was when the guidewire or ballon passed the lesion and the blood flow was regained, and another was the time before the stent was implanted.

DRUG

Saline (NaCl 0,9 %) (placebo)

In the control group, 3ml saline was given intracoronary through the guiding catheter within 30 seconds at the same time points in nicorandil group.

All Listed Sponsors
lead

China National Center for Cardiovascular Diseases

OTHER_GOV