494
Participants
Start Date
September 12, 2023
Primary Completion Date
March 1, 2025
Study Completion Date
June 1, 2025
transcutaneous auricular vagus nerve stimulation
"1. Prior to execution: Remove jewelry (such as earrings) that may interfere with the electrode placement; attach the electrodes to the tragus of the left ear; feed the wires over the right shoulder from the back of the neck, and then turn on the device.~2. Initiate stimulation: Establish the following parameters: 200 μs pulse width, 30 Hz frequency, 0-36 mA current intensity (modify to the most appropriate stimulation intensity based on the patient's pain perception), and one-hour timing. Next, begin the stimulation.~3. Stimulation end: After an hour, the device will be automatically switched off. And the procedure is finished."
sham transcutaneous auricular vagus nerve stimulation
"1. Prior to execution: Remove jewelry (such as earrings) that may interfere with the electrode placement; attach the electrodes to the tragus of the left ear; feed the wires over the right shoulder from the back of the neck, and then turn on the device.~2. Initiate stimulation: Establish the following parameters: 200 μs pulse width, 30 Hz frequency, 0-36 mA current intensity (modify to the most appropriate stimulation intensity based on the patient's pain perception). Next, turn off the stimulation,and one-hour timing.~3. Stimulation end: After an hour, the device will be removed and the procedure is finished."
RECRUITING
First Hospital of China Medical University, Shenyang
Guozhe Sun
OTHER