Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking Buprenorphine

PHASE4RecruitingINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2027

Conditions
Opioid Use Disorder
Interventions
DRUG

Morphine

200 mcg intrathecal morphine

DRUG

Bupivacaine

Intrathecal 0.75% bupivacine in 8.25% dextrose (Dose determined by weight, height, gestational age)

DRUG

Fentanyl

15 mcg intrathecal fentanyl

DRUG

Hydromorphone

100 mcg intrathecal hydromorphone

Trial Locations (1)

27599

RECRUITING

University of North Carolina at Chapel Hill, Chapel Hill

All Listed Sponsors
lead

University of North Carolina, Chapel Hill

OTHER