A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

71

Participants

Timeline

Start Date

January 8, 2025

Primary Completion Date

October 31, 2027

Study Completion Date

January 31, 2028

Conditions
Metastatic Prostate CancerMetastatic Head and Neck Squamous Cell CarcinomaMetastatic Pancreatic Cancer
Interventions
DRUG

Evofosfamide

Evofosfamide administered on Days 1 and 8 of Cycles 1, 2, and 3.

DRUG

Zalifrelimab

Zalifrelimab administered on Day 8 of Cycles 1, 3, and 5.

DRUG

Balstilimab

Balstilimab administered every 2 weeks beginning on Day 8 of Cycle 1.

Trial Locations (1)

77030

RECRUITING

MD Anderson Cancer Center, Houston

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Agenus Inc.

INDUSTRY

lead

ImmunoGenesis

INDUSTRY

NCT06782555 - A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab | Biotech Hunter | Biotech Hunter