InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Treatment Resistant Depression
Interventions
DRUG

Ketamine

Standard-of-care ketamine treatment in the outpatient setting: 0.5 mg/kg IV infused over 45 minutes (with monitoring up to 90 minutes) per session, with 2 sessions per week for 2 weeks (total 4 treatments).

DEVICE

Oculus VR headset

Immersion in 45 minutes of virtual environments using the Oculus VR headset during each ketamine infusion.

Trial Locations (1)

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

All Listed Sponsors
lead

Sunnybrook Health Sciences Centre

OTHER