NCT06779890View on ClinicalTrials.gov

Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome

PHASE4RecruitingINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

May 12, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Brain Edema Caused by DrugsCerebral Oxygenation
Interventions
DRUG

Sevoflurane

Sevoflurane will be administered at concentrations maintaining MAC= 0.8 for the first 60 minutes , MAC=1.2 for the next 60 minutes and MAC= 0.8 until surgery completion.

DRUG

Desflurane

Desflurane will be administered at concentrations maintaining MAC= 0.8 for the first 60 minutes , MAC=1.2 for the next 60 minutes and MAC= 0.8 until surgery completion.

Trial Locations (2)

54645

RECRUITING

AHEPA University Hospital, Thessaloniki

56224

RECRUITING

Aristotle University of Thessaloniki, Thessaloniki

All Listed Sponsors
lead

Georgia Tsaousi

OTHER