10
Participants
Start Date
September 1, 2025
Primary Completion Date
April 28, 2026
Study Completion Date
May 22, 2026
High efficiency particulate air filtration system (nightly administration)
Portable air purifier is programmed to provide a dose of filtered air at 275 m³/h nightly for at least 7 hours consecutive within a time window between 10:00 p.m. and 10:00 a.m. Air purifier is set up with active filters (HyperHEPA technology). Dose adjustments are permitted in the study where noise disturbance is an issue for participants. The air filtration therapy will be delivered in doses decreasing sequentially in terms of speed mode. Participants will be instructed to keep doors and windows of the bedroom closed during each session at night, and to follow a similar bedtime routine.
High efficiency particulate air filtration system (nightly and daily administration)
Portable air purifier set up with active filters (HyperHEPA technology) is continuously in operation (24 hours for 14 days) at 275 m³/h in bedrooms with the door and windows closed. During this open-labell phase, the participants will be asked to remain in the bedroom for as long as possible and to keep an activity log for the outdoor locations. Dose adjustments are permitted.
Air filtration system without filters (sham)
Portable air purifier is programmed to provide a dose of filtered air at 275 m³/h nightly for at least 7 hours consecutive within a time window between 10:00 p.m. and 10:00 a.m. Air purifier is set up with a sham filter, which is identical in appearance and noise as the HyperHEPA filter (active filter) when the air purifier is in operation. Dose adjustments are permitted in the study where noise disturbance is an issue for participants.
RECRUITING
Mallilla Primary Care Practice, Valencia
RECRUITING
Russafa Primary Care Practice, Valencia
IQAir AG
UNKNOWN
PremaLabs Diagnostics, Ltd
UNKNOWN
A&D Instruments, Ltd
UNKNOWN
Lansion Biotechnology Co. Ltd
UNKNOWN
University College, London
OTHER