Physiological Effect High-flow Tracheal Oxygen on Viscosity of Airway Mucus and Respiratory Effort in Patients Weaning from Invasive Mechanical Ventilation

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 6, 2025

Primary Completion Date

January 31, 2025

Study Completion Date

July 1, 2026

Conditions
Weaning from Mechanical VentilationTracheostomy WeaningRespiratory Failure
Interventions
DEVICE

Oxygen therapy

All patients are subject to both oxygen therapy groups in this randomized cross-over study. Study measurements are performed during several different disconnection sessions. Disconnection sessions can either be short (\<90 min) or long (12 hours). Both short and long disconnection sessions are performed twice; once with conventional oxygen, and once with high-flow tracheal oxygen as respiratory support.

Trial Locations (1)

3015

RECRUITING

Erasmus Medical Center, Rotterdam

All Listed Sponsors
collaborator

Fisher and Paykel Healthcare

INDUSTRY

lead

Henrik Endeman

OTHER