NCT06775145 - Therapeutic Effect of Neuromodulation on Anxiety Disorders by High-Definition Transcranial Electrical Stimulation | Biotech Hunter

Enrollment

100

Participants

Timeline

Start Date

February 3, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions

Generalized Anxiety Disorder (GAD)

Interventions

DEVICE

HD-R_cDC+cTBS & sham-L_aDC+iTBS

HD-tES inhibitory waveform (cDC+cTBS) applied to the right dorsolateral prefrontal cortex (DLPFC) for 10 minutes, followed by sham excitatory waveform (aDC+iTBS) stimulation applied to the left DLPFC for 10 minutes.

DEVICE

sham-R_cDC+cTBS & HD-L_aDC+iTBS

Sham inhibitory waveform (cDC+cTBS) stimulation applied to the right DLPFC for 10 minutes, followed by HD-tES excitatory waveform (aDC+iTBS) applied to the left DLPFC for 10 minutes.

DEVICE

HD-R_cDC+cTBS & HD-L_aDC+iTBS

HD-tES inhibitory waveform (cDC+cTBS) applied to the right DLPFC for 10 minutes, followed by HD-tES excitatory waveform (aDC+iTBS) applied to the left DLPFC for 10 minutes.

DEVICE

sham-R_cDC+cTBS & sham-L_aDC+iTBS

Sham inhibitory waveform (cDC+cTBS) stimulation applied to the right DLPFC for 10 minutes, followed by sham excitatory waveform (aDC+iTBS) stimulation applied to the left DLPFC for 10 minutes.

All Listed Sponsors

lead

National Taiwan University Hospital

OTHER