Association of Thoraco-mediastinal Radiotherapy With Maintenance Immunotherapy Treatment With Atezolizumab

PHASE2RecruitingINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

December 15, 2021

Primary Completion Date

December 15, 2026

Study Completion Date

December 15, 2026

Conditions
Small Cell Lung Cancer
Interventions
RADIATION

Thoracic radiotherapy

Thoracic radiotherapy using 4D technique by irradiating the initial sites of disease (primary tumor and involved hilo-mediastinal lymph nodes). The treatments must be provided with the modulated intensity technique (IMRT or VMAT), treatments with conformal technique (3DCRT) are not permitted, where necessary, the Simultaneous Integrated Boost (SIB) technique can be used.

DRUG

Atezolizumab 1200 mg e.v. q21

Radiotherapy treatment associated with Atezolizumab 1200 mg i.v. q21 administered according to clinical practice

Trial Locations (1)

00144

RECRUITING

"Regina Elena National Cancer Institute", Rome

All Listed Sponsors
lead

Regina Elena Cancer Institute

OTHER