NCT06771492View on ClinicalTrials.gov

Efficacy of Antibiotic Treatment for Patients With Chronic Low Back Pain and Modic Type I Changes - Randomized Placebo-controlled Trial

PHASE3RecruitingINTERVENTIONAL
Enrollment

204

Participants

Timeline

Start Date

April 2, 2025

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
MSK ConditionsChronic Low Back Pain (CLBP)Modic Changes
Interventions
DRUG

Amoxicillin

Antibiotic treatment (amoxicillin) with a dosage of 1000 mg (3 times a day) for a period of 100 days

OTHER

Placebo

Placebo with a dose of 1000 mg (3 times a day) for a period of 100 days

Trial Locations (1)

3015 GD

RECRUITING

Erasmus Medical Center, Rotterdam

All Listed Sponsors
collaborator

Erasmus University Rotterdam

OTHER

lead

Bart Koes

OTHER