Genetic Carbohydrate Maldigestion As Model to Study Food Hypersensitivity Mechanism (WORK PACKAGE 2)

Not yet recruitingOBSERVATIONAL
Enrollment

80

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

March 31, 2026

Conditions
Sucrase Isomaltase Deficiency
Interventions
OTHER

Blood, stool and saliva collection

Blood, stool and saliva collection

OTHER

Questionnaire completion

"Questionnaire on:~* Hospital Anxiety and Depression Score (HADS) for adults~* Total glucose and fructose and excess fructose, lactose, sorbitol, mannitol, oligosaccharides (Fructans and GOS) as measured by CNAQ questionnaire for adults and children~* Patient Health Questionnaire 12 (PHQ-12) Somatic Symptom scale"

DIAGNOSTIC_TEST

Magnetic Resonance Imaging (MRI) and Breath test

MRI scans and breath test samples collected after drink test with sucrose

Trial Locations (1)

NG7 2UH

University of Nottingham, Nottingham

All Listed Sponsors
collaborator

cic bioGune

UNKNOWN

collaborator

Institute for Clinical Molecular Biology, Christian-Albrechts-University, Kiel

UNKNOWN

collaborator

University of Veterinary Medicine Hannover

UNKNOWN

lead

University of Nottingham

OTHER