Exogenous Ketosis and Muscle Protein Synthesis During Exercise Recovery

NARecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

January 10, 2025

Primary Completion Date

October 30, 2025

Study Completion Date

October 30, 2025

Conditions
KetosisMuscle Protein SynthesisDietary ProteinsResistance Exercise
Interventions
DIETARY_SUPPLEMENT

Ketone Monoester (KET)

\- Ketone monoester supplement (R)-3-hydroxybutyl (R)-3-hydroxybutyrate based on participants' body weight (0.36g/kg body weight). The ketone brand name: delta G Oxford Ketone Ester

DIETARY_SUPPLEMENT

Ketone Monoester + Whey Protein (KET+PRO)

"* Ketone monoester supplement (R)-3-hydroxybutyl (R)-3-hydroxybutyrate based on participants' body weight (0.36g/kg body weight)~* 25g Whey Protein~* L-\[ring-2H5\]-phenylalanine tracer (enriched to 4%)"

DIETARY_SUPPLEMENT

Whey Protein (PRO)

"* 25g Whey Protein~* L-\[ring-2H5\]-phenylalanine tracer (enriched to 4%)"

DIETARY_SUPPLEMENT

Flavour matched placebo (CON)

\- Flavoured water (non-caloric bitter + citrus flavours)

OTHER

Resistance exercise

\- 8 sets of 10 reps at 90% of 10- repetition maximum (10-RM) of unilateral leg extension with 90 seconds rest in between sets.

Trial Locations (1)

H2W 1S4

RECRUITING

McGill University, Montreal

All Listed Sponsors
lead

McGill University

OTHER