Morbid Obesity and Severe Knee Osteoarthritis - Which Should Be Treated First?

NANot yet recruitingINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2027

Conditions
Osteoarthritis of KneeArthroplasties, Knee ReplacementSleeve Gastrectomy
Interventions
PROCEDURE

laparoscopic sleeve gastrectomy

Participants undergoing laparoscopic sleeve gastrectomy (LSG) will be clinically assessed and provided consent to this procedure by one of the bariatric surgeons affiliated with the bariatric surgery program. LSG will be performed at a local tertiary care hospital as either a day procedure or as an overnight stay if medically indicated. Patients will be discharged once they can tolerate a liquid diet. Patients will then attend regular follow-ups with their surgeons and the bariatric surgery program, in accordance with a standardized clinical pathway protocol.

PROCEDURE

total knee arthroplasty

Patients undergoing unilateral total knee arthroplasty (TKA) will be clinically assessed and provided consent to their procedure by an orthopaedic surgeon trained in joint arthroplasty. TKA will be performed at a local tertiary care hospital as either a day procedure or as an overnight stay if medically indicated. Patients will be discharged once physiotherapy clears them. Patients will attend regular follow-ups with their surgeon in accordance with a standardized clinical pathway protocol.

Trial Locations (2)

A1B3X5

Health Sciences Centre, St. John's

A1C5B8

St. Clare's Mercy Hospital, St. John's

All Listed Sponsors
lead

Memorial University of Newfoundland

OTHER

NCT06767787 - Morbid Obesity and Severe Knee Osteoarthritis - Which Should Be Treated First? | Biotech Hunter | Biotech Hunter