Ivonescimab Combined With Chemotherapy for the Treatment of Leptomeningeal Metastases Failed to EGFR-TKIs

NANot yet recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions

NSCLCChemotherapyLeptomeningeal MetastasesEGFR-TKIAK112

Interventions

DRUG

Ivonescimab combined with chemotherapy

Ivonescimab combined with chemotherapy. The specific chemotherapy regimen is based on the real world.

All Listed Sponsors

collaborator

Henan Cancer Hospital

OTHER_GOV

collaborator

Three Gorges Hospital of Chongqing University

OTHER

lead

Jiangsu Province Nanjing Brain Hospital

OTHER