Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

February 10, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

January 31, 2026

Conditions
Laparoscopic Donor NephrectomyPerioperative Pain Management
Interventions
PROCEDURE

Spinal anesthesia adjuvant

Patients in this arm will receive 10 mg 0.5% hyperbaric Bupivacaine, 100 mcg Morphine, 100 mcg Sulfas Atropine, and 0.9% normal saline to total volume of 4 ml before induction of anesthesia.

PROCEDURE

Quadratus Lumborum Block (QLB)

Patients in this arm will receive quadratus lumborum block with 20-30 ml of 0.25% Bupivacaine after induction of anesthesia and after operation.

PROCEDURE

General Anesthesia

The subject will undergo preoxygenation with 100% oxygen for 3 minutes. Following preoxygenation, anesthesia induction will be performed using lidocaine at a dose of 1.5 mg/kg, fentanyl at 1.5 mcg/kg, and propofol at 2.0 mg/kg. Once the subject is adequately sedated, baseline neuromuscular monitoring using the train-of-four (TOF) technique will be conducted, followed by the administration of rocuronium at a dose of 0.8 mg/kg. Endotracheal intubation will be performed using direct laryngoscopy once the TOF value reaches 0, utilizing an appropriately sized endotracheal tube (ETT). Ten milligrams of intravenous dexamethasone is administered after induction.

Trial Locations (1)

10430

RECRUITING

RSUP dr. Cipto Mangunkusumo, Jakarta Pusat

All Listed Sponsors
collaborator

Dr Cipto Mangunkusumo General Hospital

OTHER

lead

Indonesia University

OTHER