Adjunctive Effect of Photodynamic Therapy on Halitosis

NAEnrolling by invitationINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 8, 2025

Primary Completion Date

February 22, 2025

Study Completion Date

June 25, 2025

Conditions
PeriodontitisHalitosis
Interventions
RADIATION

Full-mouth scaling combined with antimicrobial photodynamic therapy

After full-mouth scaling procedures antimicrobial photodynamic therapy was carried out using a laser-activated disinfection device with a red laser emission (wavelength: 630 nm, irradiance: 2000-4000 mW/cm², spot size at the probe tip: 8 mm diameter) and high-viscosity methylene blue gel (0.1 mg/mL) which was applied at six spots on the tongue dorsum. Antimicrobial photodynamic therapy was also applied iIn sites with altered periodontal pocket depth (≥ 4mm). The dye remained in the pockets for 10 minutes to ensure full absorption and its excess was rinsed with sterile saline after laser exposure.

PROCEDURE

full-mouth scaling

Full-mouth scaling within 24 hours, divided into two sessions of ultrasonic instrumentation followed by manual supra- and subgingival scaling and root planing. Tongue cleaning was performed with a tongue scraper.

Trial Locations (1)

31270-901

Federal University of Minas Gerais, Dental School, Belo Horizonte

All Listed Sponsors
lead

Federal University of Minas Gerais

OTHER