NCT06758609View on ClinicalTrials.gov

To Assess the Effectiveness and Safety of Catheter-based Focal Intracranial Hypothermia Combined with Endovascular Reperfusion Therapy for Patients with Acute Anterior Circulation Large Artery Occlusion

NARecruitingINTERVENTIONAL
Enrollment

262

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

March 30, 2026

Study Completion Date

June 30, 2026

Conditions
Acute Cerebrovascular AccidentAcute Ischemic StrokeInternal Carotid ArteryMiddle Cerebral Artery Occlusion
Interventions
PROCEDURE

Mechanical thrombectomy

Mechanical thrombectomy

DRUG

4°C saline infusion

Patients received a total of 350 ml of 4°C saline infusion in addition to mechanical thrombectomy (MT).

DRUG

Normothermic saline infusion

Patients received a total of 350 ml of roomtemperature saline infusion in addition to mechanical thrombectomy (MT).

Trial Locations (1)

510317

RECRUITING

Guangdong Second Provincial General Hospital, Guangzhou

All Listed Sponsors
lead

Guangdong Second Provincial General Hospital

OTHER