The Effect and Safety of Combined Anti-platelet Treatment in Acute Ischemic Stroke Due to Large Artery Atherosclerosis

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,340

Participants

Timeline

Start Date

July 10, 2025

Primary Completion Date

March 31, 2028

Study Completion Date

March 31, 2028

Conditions
Cerebral InfarctionStenosis Artery
Interventions
DRUG

Aspirin

"Aspirin 100mg qd (21days)~* In case of stenting, aspirin will be added to cilostazol and clopidogrel until 90 days after stenting.~* Route: per oral. IMP can be taken with or without food.~* Frequency: once daily (qd)"

DRUG

Clopidogrel

"Clopidogrel 75mg qd (180days)~* Route: per oral. IMP can be taken with or without food.~* Frequency: once daily (qd)"

DRUG

Cilostazol

"Cilostazol SR 100mg x 2cap (180days)~* Route: per oral. IMP can be taken with or without food.~* Frequency: once daily (qd)"

DRUG

Placebo

"Placebo x 2cap (180days)~* Route: per oral. IMP can be taken with or without food.~* Frequency: once daily (qd)"

Trial Locations (24)

13620

NOT_YET_RECRUITING

Seoul National University Bundang Hospital, Gyeonggi-do

21565

RECRUITING

Gachon University Gil Medical Center, Incheon

05505

RECRUITING

Asan Medical Center, Seoul

Unknown

RECRUITING

Pusan National University Hospital, Busan

NOT_YET_RECRUITING

Chungbuk National University Hospital, Cheongju-si

NOT_YET_RECRUITING

Kyungpook National University Chilgok Hospital, Daegu

NOT_YET_RECRUITING

Chungnam National University Hospital, Daejeon

NOT_YET_RECRUITING

Eulji University Hospital, Daejeon

RECRUITING

Chonnam National University Hospital, Gwangju

NOT_YET_RECRUITING

Hallym University Medical Center, Gyeonggi-do

NOT_YET_RECRUITING

Hanyang University Guri Hospital, Gyeonggi-do

NOT_YET_RECRUITING

Korea University Ansan Hospital, Gyeonggi-do

NOT_YET_RECRUITING

Inha University Hospital, Incheon

NOT_YET_RECRUITING

Jeju National University Hospital, Jeju City

NOT_YET_RECRUITING

Jeonbuk National University Hospital, Jeonju

NOT_YET_RECRUITING

Ewha Womans University Seoul Hospital, Seoul

NOT_YET_RECRUITING

Hanyang University Seoul Hospital, Seoul

NOT_YET_RECRUITING

Korea University Guro Hospital, Seoul

NOT_YET_RECRUITING

Kyung Hee University Hospital at Gangdong, Seoul

NOT_YET_RECRUITING

Kyung Hee University Hospital, Seoul

NOT_YET_RECRUITING

Samsung Medical Center, Seoul

NOT_YET_RECRUITING

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul

NOT_YET_RECRUITING

Yonsei University Health System, Gangnam Severance Hospital, Seoul

NOT_YET_RECRUITING

Pusan National University Yangsan Hospital, Yangsan

All Listed Sponsors
collaborator

Korea Otsuka Pharmaceutical Co., Ltd.

INDUSTRY

lead

Asan Medical Center

OTHER

NCT06757764 - The Effect and Safety of Combined Anti-platelet Treatment in Acute Ischemic Stroke Due to Large Artery Atherosclerosis | Biotech Hunter | Biotech Hunter