Evaluate the Efficacy of Radiofrequency Ablation/Vertebroplasty with or Without SBRT for Treating Painful Spinal Vertebral Metastases

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Spinal MetastasesLocal ControlPain Cancer
Interventions
RADIATION

Radiofrequency Ablation (RFA)/Vertebroplasty+Stereotactic Radiotherapy

"All patients received OsteoCool™ radiofrequency ablation + vertebroplasty for spinal metastatic tumors at the Department of Bone Oncology, Shanghai First People's Hospital.~Standard Control Group: Patients received SBRT (Stereotactic Body Radiation Therapy) from the Department of Radiation Oncology 2-3 weeks post-surgery. This included pre-radiation positioning, mold preparation, and radiation therapy. After radiation therapy, patients rested for 2 weeks before resuming their original anti-tumor treatment and starting follow-up.SBRT therapy was administered according to the recommendations, using one of the following dose and fractionation schemes: 4 sessions of 24 Gy, 5 sessions of 30 Gy, 6 sessions of 36 Gy, or 7 sessions of 42 Gy."

PROCEDURE

Experimental

patients received OsteoCool™ radiofrequency ablation+vertebroplasty for spinal metastatic tumors at the Department of Bone Oncology, Shanghai First People's Hospital. patients continued their original anti-tumor treatment within 1-2 weeks based on their recovery. No further local intervention was performed at the surgical site, and normal follow-up was started.

Trial Locations (1)

200092

Shanghai General Hospital, Shanghai

All Listed Sponsors
collaborator

The Third Affiliated Hospital of Southern Medical University

OTHER_GOV

collaborator

Peking University People's Hospital

OTHER

lead

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER