Effect of Low Tidal Volume Ventilation on Postoperative Delirium

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Postoperative Delirium (POD)Cardiopulmonary BypassLow Tidal Volume VentilationCognitive Dysfunction, Postoperative
Interventions
PROCEDURE

Group B: Low tidal volume

In the LTV group, mechanical ventilation will be maintained with low tidal volume parameters after the aortic cross-clamp procedure. This intervention includes a tidal volume of 3-4 mL/kg, respiratory rate of 12-14 breaths/min, PEEP of 5-8 cmH₂O, and FiO₂ of 50%. Minute ventilation (MV) will not exceed 12 L, and the parameters are adjusted according to ideal body weight. This group is designed to evaluate the protective effects of low tidal volume ventilation during surgery.

Trial Locations (1)

42030

RECRUITING

Konya City Hospital, Konya

All Listed Sponsors
lead

Nevsehir Public Hospital

OTHER_GOV