High Fat Diet for Cardiac Metabolic Reprogramming

NANot yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

July 31, 2026

Conditions
Hearth Failure Secondary to Non-ischemic DCM with Reduced LVEF (≤40%)
Interventions
OTHER

High fat diet

Weekly isocaloric dietary profile, with total daily energy intake distributed as follows: 70% from fats, primarily sourced from nuts, extra virgin olive oil, avocados, and animal fats from fish and cheese; protein intake of 0.8-1.2 g per kg body weight (10-20%); and the remaining calories from carbohydrates (10-20%).

OTHER

Standard diet

Weekly isocaloric dietary profile, with total daily energy intake distributed as follows: 30% from fats, primarily sourced from nuts, extra virgin olive oil, avocados, and animal fats from fish and cheese; protein intake of 0.8-1.2 g per kg body weight (10-20%); and 50-60% from carbohydrates.

All Listed Sponsors
collaborator

INSTITUTO DE SALUD CARLOS III (ISCIII)

UNKNOWN

collaborator

Puerta de Hierro Majadahonda University Hospital

UNKNOWN

collaborator

Nicole Karam, European Hospital Georges Pompidou, Paris, France

UNKNOWN

collaborator

Carol Davila University of Medicine and Pharmacy Bucharest

UNKNOWN

lead

Azienda Ospedaliero-Universitaria Careggi

OTHER

NCT06747429 - High Fat Diet for Cardiac Metabolic Reprogramming | Biotech Hunter | Biotech Hunter