Comparative Efficacy and Safety of Extensive Electro-Anatomical Guided Pulsed Field Ablation Versus Radiofrequency Ablation in Persistent Atrial Fibrillation

NANot yet recruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Atrial Fibrillation (AF)
Interventions
PROCEDURE

Pulsed field ablation

Utilizing pulsed field ablation (PFA), combining pulmonary vein isolation (PVI) with extensive ablation based on anatomical landmarks (including posterior wall box isolation) and electrogram-guided ablation.

PROCEDURE

Radiofrequency ablation alone

Using conventional radiofrequency ablation technology, combines pulmonary vein isolation (PVI) with extensive ablation based on anatomical landmarks (including posterior wall box isolation) and electrogram-guided ablation

Trial Locations (1)

200000

No. 241, West Huaihai Road, Shanghai

All Listed Sponsors
collaborator

Albert Einstein College of Medicine and Montefiore Medical Center

UNKNOWN

collaborator

Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine

UNKNOWN

collaborator

Shandong University of Traditional Chinese Medicine

OTHER

collaborator

Yuhuan Second People's Hospital

UNKNOWN

collaborator

Changshu Hospital of Traditional Chinese Medicine

OTHER

collaborator

The PLA Navy Anqing Hospital

UNKNOWN

collaborator

Jinan People's Hospital

UNKNOWN

collaborator

Xuzhou Central Hospital

OTHER

lead

Shanghai Chest Hospital

OTHER

NCT06745167 - Comparative Efficacy and Safety of Extensive Electro-Anatomical Guided Pulsed Field Ablation Versus Radiofrequency Ablation in Persistent Atrial Fibrillation | Biotech Hunter | Biotech Hunter