Detection of Sepsis Occurrence by Using Blood Fluorescence

RecruitingOBSERVATIONAL
Enrollment

90

Participants

Timeline

Start Date

September 9, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

October 1, 2027

Conditions
Sepsis
Interventions
DIAGNOSTIC_TEST

Blood fluorescence metabolite analyzer

This study does not involve Intervention. The fluorescence intensity quantified by the blood fluorescence metabolite analyzer does not affect or interfere with clinical diagnosis and treatment. In both the early and late stages of sepsis, a significant increase in inflammatory free radicals changes the optical properties of the patient's blood, distinguishing it from that of healthy individuals. To explore this phenomenon, 10 cc of fasting blood is drawn from patients who pass our screening criteria. This sample is then centrifuged in accordance with our detailed standard operating procedures to ready it for analysis. Subsequently, the fluorescence intensity of the blood is measured quantitatively using a precisely calibrated blood fluorometer, which is specifically designed to detect subtle variations indicative of both early and late sepsis. This entire process is executed under stringent quality control protocols to ensure the reliability and accuracy of the results.

Trial Locations (1)

510280

RECRUITING

zhujiang Hospital, Guangzhou

All Listed Sponsors
collaborator

University of Macau

OTHER

lead

Zhujiang Hospital

OTHER