The Safety and Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy for Peritoneal Metastatic Adenocarcinoma

PHASE1RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 11, 2024

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Peritoneal Carcinoma Metastatic
Interventions
DRUG

Pressurized Intraperitoneal Aerosol Chemotherapy

"The comprehensive therapeutic strategy will be modified based on the integrated 2- or 3-week systemic chemotherapies. In the interim, a total of three PIPAC procedures will be conducted for all qualifying patients.~1. PIPAC combined with 2-week systemic chemotherapies:~ PIPAC therapy will occur every four weeks, while systemic chemotherapies will be administered during the first and third weeks following the initial and second PIPAC procedures respectively.~2. PIPAC combined with 3-week systemic chemotherapies:~(1) Scheme 1: PIPAC therapy will occur every 6 weeks, with systemic chemotherapies administered during the 1st and 4th weeks following the first and second PIPAC procedures, respectively.~(2) Scheme 2: PIPAC therapy will occur every 6 weeks, while systemic chemotherapies will be administered in the 2nd and 5th weeks following the initial and second PIPAC procedures, respectively."

Trial Locations (1)

510080

RECRUITING

Guangdong Provincial People's Hospital, Guangzhou

All Listed Sponsors
collaborator

Tianjin Third Central Hospital

OTHER

collaborator

Peking University Cancer Hospital & Institute

OTHER

collaborator

Second Affiliated Hospital of Guangzhou Medical University

OTHER

collaborator

The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine

OTHER

collaborator

Henan Cancer Hospital

OTHER_GOV

collaborator

Tongji Hospital

OTHER

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

Jiangxi Provincial Cancer Hospital

OTHER

collaborator

The First Affiliated Hospital of Air Force Medicial University

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

Southern Medical University, China

OTHER

collaborator

Affiliated Hospital of Qinghai University

OTHER

collaborator

Ruijin Hospital

OTHER

collaborator

Shenzhen Second People's Hospital

OTHER

collaborator

West China Hospital

OTHER

collaborator

Tianjin Nankai Hospital

OTHER

collaborator

Wannan Medical College Yijishan Hospital

OTHER

collaborator

Second Affiliated Hospital of Wenzhou Medical University

OTHER

collaborator

Changzhi People's Hospital

OTHER

collaborator

First Hospital of China Medical University

OTHER

collaborator

Xiangya Hospital of Central South University

OTHER

collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

collaborator

Sun Yat-sen University

OTHER

collaborator

Fujian Medical University Union Hospital

OTHER

lead

Guangdong Provincial People's Hospital

OTHER