Apixaban Prophylaxis for Prevention of Left Ventricular Thrombus Following Anterior Myocardial Infarction

PHASE3RecruitingINTERVENTIONAL
Enrollment

472

Participants

Timeline

Start Date

December 2, 2024

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Acute Myocardial Infarction of Anterior WallLeft Ventricular ThrombusProphylaxis
Interventions
DRUG

Apixaban 2.5 MG PO BID

Patients randomized to the treatment arm will be given Apixaban 2.5 mg twice daily and DAPT (aspirin (75 mg) + clopidogrel (75 mg)) for four weeks in addition to other guideline directed medical therapy (GDMT). After 4 weeks, treatment group will be switched to DAPT.

DRUG

Control (Standard treatment)

DAPT plus guideline directed medical therapy

Trial Locations (1)

Unknown

RECRUITING

NICVD Pakistan, Karachi

All Listed Sponsors
lead

National Institute of Cardiovascular Diseases, Pakistan

OTHER