Pro-Epileptic Effects of IV Ketamine

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

August 30, 2025

Study Completion Date

August 30, 2025

Conditions
EpilepsySeizure
Interventions
DRUG

Ketamine

The Ketamine group received IV ketamine at a titrated dose of 0.5-1.0 mg/kg with IV fentanyl, administered in small incremental boluses of 25-50 mcg to ensure adequate analgesia.

DRUG

Midazolam

The Midazolam group received IV midazolam at a titrated dose of 0.15-0.40 mg/kg with IV fentanyl, administered in small incremental boluses of 25-50 mcg to ensure adequate analgesia.

DRUG

Propofol

The Propofol group received IV propofol at a titrated dose of 0.5-1.0 mg/kg with IV fentanyl, administered in small incremental boluses of 25-50 mcg to ensure adequate analgesia.

Trial Locations (1)

34265

Haseki Training and Research Hospital, Istanbul

All Listed Sponsors
lead

Haseki Training and Research Hospital

OTHER

NCT06741930 - Pro-Epileptic Effects of IV Ketamine | Biotech Hunter | Biotech Hunter