Assessing the Relationship Between Symptoms and Mitral Regurgitnant. Severity

RecruitingOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

January 2, 2025

Primary Completion Date

January 2, 2027

Study Completion Date

May 2, 2027

Conditions
Mitral Insufficiency
Interventions
DIAGNOSTIC_TEST

Pressure volume loop evaluation

During the left heart catheterization there are catheters which are introduced into the left ventricle to measure left ventricular pressures and into the coronary arteries to assess their patency. This study will require the placement of an additional specialized catheter made into the left ventricle to measure the change of pressure and volume during the cardiac cycle. This will allow the measurement of heart muscle stiffness.

DIAGNOSTIC_TEST

cardiovascular magnetic resonance imaging

Patients will undergo standard cardiovascular magnetic resonance imaging of their heart to measure their heart size, heart function, and severity of mitral regurgitation. In addition, contrast will be administered and heart tissue will be assessed for scarring or fibrosis.

DIAGNOSTIC_TEST

Cardiopulmonary exercise testing (CPET)

A CPET will be performed to objectively measure a patient ability to perform exercise.

DIAGNOSTIC_TEST

Kansas City Cardiomyopathy Questionairre

This is a short questionnaire which objectively quantifies symptom burden

Trial Locations (1)

07960

RECRUITING

Morristown Medical Center, Morristown

Sponsors
All Listed Sponsors
lead

Atlantic Health System

OTHER