Efficacy of Dexmedetomidine As an Adjuvant to Bupivacaine in Pericapsular Nerve Group Block in Hip Replacement Surgeries

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

March 31, 2027

Conditions
PENG Block
Interventions
PROCEDURE

Ultrasound guided Pericapsular Nerve Group Block

"With the patient in the supine position and the leg slightly abducted, a curvilinear transducer (2.5-7.5 MHz) is prepared with sterile conduction gel and covered with a sterile probe cover. The transducer is placed transversely over the anterior superior iliac spine (ASIS), then aligned with the pubic ramus and rotated approximately 45° parallel to the inguinal crease. The probe is slid medially to identify key landmarks: the anterior inferior iliac spine (AIIS), iliopubic eminence (IPE), iliopsoas tendon, femoral artery, and femoral nerve. Sliding the probe distally or tilting caudally exposes the femoral head.~A 20-22 gauge echogenic needle (100 mm) is inserted in-plane from lateral to medial, targeting the plane between the psoas tendon and the pubic ramus. the anesthetic agent is deposited to lift the psoas tendon while avoiding tendon puncture."

DRUG

Isobaric Bupivacaine 0. 25%

group c will receive PENG block with only 20ml isobaric bupivacaine 0.25%

DRUG

20 ml isobaric bupivacaine 0.25% and 1.5μg/kg dexmedetomidine

group D will receive PENG block with 20 ml isobaric bupivacaine 0.25% and 1.5μg/kg dexmedetomidine

DEVICE

the ultrasound machine with curvilinear transducer (high -frequency probe, 2.5Mhz to 7.5Mhz)

the two groups will receive the PENG block under ultrasound guidance

DEVICE

a standard echogenic 20-22 gauge 100mm needle

the two groups will receive the PENG block using a standard echogenic 20-22 gauge 100mm needle

All Listed Sponsors
lead

Assiut University

OTHER