Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

224

Participants

Timeline

Start Date

March 15, 2025

Primary Completion Date

August 15, 2026

Study Completion Date

December 15, 2026

Conditions
Obesity and Overweight
Interventions
DRUG

NA-931

"NA-931 (oral, daily), a quadruple receptor agonist~Tirzepatide (Zepbound) placebo"

DRUG

Tirzepatide

"Tirzepatide (s.c. weekly)~* Glucagon-like peptide-1 (GLP-1) receptor agonist~* Other Names:~ * Mounjaro~ * Zepbound NA-931 Placebo (oral, daily)"

DRUG

Tirzepatide

"Tirzepatide (s.c. weekly), a Glucagon-like peptide-1 (GLP-1) receptor agonist~• Other Names:~* Mounjaro~* Zepbound~NA-931 Placebo (oral, daily)"

DRUG

NA-931

"NA-931, an oral, daily~• A quadruple receptor agonist"

DRUG

NA-931

"NA-931 (oral, daily), a quadruple receptor agonist~Tirzepatide (s.c. weekly)~* Glucagon-like peptide-1 (GLP-1) receptor agonist~* Other Names:~ * Mounjaro~ * Zepbound"

DRUG

NA-931

"NA-931 (oral daily), a quadruple receptor agonist~Tirzepatide (s.c. weekly)~* Glucagon-like peptide-1 (GLP-1) receptor agonist~* Other Names:~ * Mounjaro~ * Zepbound"

DRUG

NA-931 150 mg + no Tirzepatide

NA-931 150 mg + no Tirzepatide

DRUG

NA-931

"NA-931 (oral, daily), a quadruple receptor agonist~Tirzepatide (s.c. weekly)~* Glucagon-like peptide-1 (GLP-1) receptor agonist~* Other Names:~ * Mounjaro~ * Zepbound"

DRUG

NA-931

"NA-931 (oral, daily), a quadruple receptor agonist~Tirzepatide (s.c. weekly)~* Glucagon-like peptide-1 (GLP-1) receptor agonist~* Other Names:~ * Mounjaro~ * Zepbound"

Trial Locations (17)

1010

Biomed Research Unit-NZ-1010-114, Auckland

2025

Biomed Research Unit-NZ-2025-115, Papatoetoe

2065

Biomed Research Unit-NSW-2065-110, Saint Leonards,

2100

Biomed Research Unit-NSW-2100-109, Brookvale

3084

, Victoria, Australia, 3084 Biomed Research Unit-VIC-3084-113, Heidelberg West

3124

Biomed Research Unit-VIC-3124-112, Camberwell

3200

Hamilton, New Zealand, 3200 Biomed Research Unit-NZ-3200-116, Hamilton

4101

, Australia, 4101 Biomed Research Unit-NSW-4101-111, South Brisbane

6242

Biomed Research Unit-NZ- 6242-117, Newtown

10021

Biomed Research Unit # 10021-107, New York

32256

Biomed Research Unit # 32256-105, Jacksonville

33012

Biomed Research Unit # 33012-104, Hialeah

33461

Biomed Research Unit # 33461-106, Lake Worth

77479

Biomed Research Unit # 77479-108, Sugar Land

90067

Biomed Research Unit #90067-102, Los Angeles

92121

Biomed Research Unit # 92121-103, San Diego

94104

Biomed Research Unit # 94104-101, San Francisco

All Listed Sponsors
collaborator

Bioneurals Ltd

UNKNOWN

lead

Biomed Industries, Inc.

INDUSTRY