Gastric Emptying With Trou Normand

NANot yet recruitingINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

July 1, 2025

Study Completion Date

July 1, 2025

Conditions
Healthy Volunteer
Interventions
BEHAVIORAL

Standardised test meal

"Ingestion of a 1850 Kcal standardised 'Christmas meal' identical for each session. It will consist of the following elements Assortment of Picard Mini-Puff Pastry Aperitifs: 70g = 210 Kcal 1 glass of white wine = 85 Kcal with the aperitif~1 slice of vacuum-packed foie gras = 50 g = 230 Kcal~1 portion of turkey leg 200 g = 250 Kcal 50 g turkey cream = 130 Kcal~1 portion of steamed potatoes = 200 g = 160 Kcal~1 glass of red wine = 85 Kcal to accompany the main course~1 slice of white bread (30 g) = 55 Kcal to eat with the main course Blind test or control drink (trou normand or placebo = water) / 1 scoop of apple sorbet~1 portion 30 g camembert = 90 Kcal + White bread 1 slice (30 g) = 85 Kcal with the cheese~1 portion crumble 100 g = 250 Kcal The different elements will be weighed for each participant."

BEHAVIORAL

Ingestion of test drink

Ingestion of 2,5 cl Calvados 40° at the 70th min of the meal (before cheese and dessert)

BEHAVIORAL

Ingestion of Control drink

Ingestion of 2,5 cl water at the 70th min of the meal (before cheese and dessert)

DIAGNOSTIC_TEST

Ultrasound measurement of the antral area

Ultrasound measurement of the antral area in the volunteers lying in the 45° semi-recumbent position using an ultrasound machine (Venue Go™, GE Healthcare, Chicago, IL, USA) fitted with an abdominal transducer (probe C1-5, 1.5 to 5 MHz) to obtain a sagittal cross-section of the antrum in a plane including the left lobe of the liver and the aorta. This will be performed during the intake visit, immediately before the test drink ingestion (70th min of the meal) and 15, 45, 60, 90, 120, 150, 180 min after the end of the meal

DIAGNOSTIC_TEST

Breathalyser for measurement of the level of exhaled ethanol

Breathalyser performed during the intake visit, and 15, 90, 180 and 300 min (if the exhaled alcohol level measured at 180 minutes was greater than 0.25 mg/l of breath) after the end of the meal.

BEHAVIORAL

Discomfort

discomfort will be assessed using seven-choice Likert scales immediately before the test drink ingestion and 90 min and 180 min after the end of the standardized meal.

BEHAVIORAL

Appetite

Appetite will be assessed using seven-choice Likert scales immediately before the test drink ingestion and 90 min and 180 min after the end of the standardized meal.

DIAGNOSTIC_TEST

Pregnancy urine test carried out during the intake visit on the day of the protocol

Pregnancy urine test carried out during the intake visit on the day of the protocol for exclusion of pregnant woman.

Trial Locations (1)

69500

Hopital Femme Mère enfant, Bron

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT06728761 - Gastric Emptying With Trou Normand | Biotech Hunter | Biotech Hunter