Predictive Diagnosis of Ulcero-Necrotizing EnteroColitis in Premature Babies Using an Artificial Intelligence Approach Based on Early Analysis of the Fecal Microbiota

NARecruitingINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

April 1, 2025

Primary Completion Date

June 1, 2026

Study Completion Date

June 1, 2026

Conditions
Necrotizing Enterocolitis (NEC)Healthy Control
Interventions
DIAGNOSTIC_TEST

Ability of early digestive microbiota analysis (using artificial intelligence) to predict the occurrence of NEC diagnosed according to the Bell classification.

"The test gives us a dichotomous response (yes/no) for each stool. We will systematically analyze two stools per child, and in the event of a discrepancy, we will analyze a third to classify the child as being at risk of NEC or not.~The analysis model consists of a deep neural network that has been trained and optimized on data from international cohorts. In a local pilot study (N=20), it enabled accurate prediction for 90% of newborns."

Trial Locations (5)

Unknown

RECRUITING

CHU de Clermont-Ferrand, Clermont-Ferrand

NOT_YET_RECRUITING

CHU Grenoble, Grenoble

NOT_YET_RECRUITING

HFME, Lyon

NOT_YET_RECRUITING

Hopital Croix Rousse, Lyon

RECRUITING

CHU Saint Etienne, Saint-Etienne

All Listed Sponsors
lead

University Hospital, Clermont-Ferrand

OTHER