NCT06725277View on ClinicalTrials.gov

The OBSERVE Protocol

RecruitingOBSERVATIONAL
Enrollment

450

Participants

Timeline

Start Date

January 21, 2024

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2029

Conditions
Major Depression Disorder
Interventions
DRUG

Spravato

Intranasal esketamine

DRUG

IV Ketamine

IV ketamine

Trial Locations (6)

30322

RECRUITING

Emory University, Atlanta

48104

RECRUITING

University of Michigan, Ann Arbor

73160

RECRUITING

LifeStance Health, Moore

77401

RECRUITING

Houston Center for Advanced Psychiatric Treatment, Bellaire

06461

RECRUITING

Mood Institute, Milford

06512

RECRUITING

Yale School of Medicine, New Haven

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

Yale University

OTHER