GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification

PHASE4RecruitingINTERVENTIONAL

Enrollment

7,435

Participants

Timeline

Start Date

July 9, 2025

Primary Completion Date

June 30, 2032

Study Completion Date

October 31, 2032

Conditions

Primary PreventionVascular Calcification

Interventions

DRUG

Pitavastatin 4mg and ezetimibe 10mg, taken once daily

Intensive lipid-lowering therapy without aspirin

DRUG

Pitavastatin 2 mg with aspirin 100 mg, taken once daily.

Moderate-intensity lipid-lowering therapy with aspirin

Trial Locations (1)

RECRUITING

Asan Medical Center, Seoul