Synbiotics for the Management of Malnutrition (Children)

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 7, 2017

Primary Completion Date

August 11, 2017

Study Completion Date

October 19, 2017

Conditions
Severe Acute Malnutrition
Interventions
DIETARY_SUPPLEMENT

Standard therapeutic foods

All children were initially fed F-75 (75 kcal/ 100mL) therapeutic milk (Phase I) and then progressed to F-100 (100 kcal/ 100mL) (Phase II) and Plumpy'nuts (F-100 in spread form with iron fortification) (Phase III) with follow-up for 48 days

COMBINATION_PRODUCT

Therapeutic foods plus Synbiotics

the intervention group received therapeutic foods plus synbiotics containing Oligomate that was fortified in F75 at the rate of 7.5 g/L containing 4.1 g/L GOS for 1 g/100 kcal dose and at the rate of 11.5 g/L containing 6.1 g/L GOS for 1.5 g/100 kcal dose while in F100 and Plumpy'nuts it was fortified at the rate of 10 g/L containing 5.5 g/L GOS for 1 g/100 kcal dose and at the rate of 15 g/L containing 8.25 g/L GOS for 1.5 g/100 kcal dose and Resiton (Lactobacillus paracasei sbsp. paracasei) 3 billion cfu/day and 6 billion cfu/day that were mixed in different combinations.

Trial Locations (1)

54000

Nutrition Rehabilitation Unit (NRU), Department of Social & Preventive Pediatrics, Mayo Hospital,, Lahore

All Listed Sponsors
lead

University of Veterinary and Animal Sciences, Lahore - Pakistan

OTHER

NCT06722404 - Synbiotics for the Management of Malnutrition (Children) | Biotech Hunter | Biotech Hunter