40
Participants
Start Date
October 1, 2023
Primary Completion Date
November 30, 2023
Study Completion Date
November 30, 2023
nerve block with 0.5% ropivacaine
Compared to active comparator arm, the experimental arm received the same procedure except in the analgesia maintenance which was performed by nerve block of the scalp using 0.5% ropivacaine. However, during craniotomy surgery, pain may occur in patients in any arms. This was defined as a sudden rise of heart rate and blood pressure higher than 20% from baseline. In that case, a bolus of fentanyl was administered as rescue analgesia.
General anesthesia and opioids (fentanyl, propofol, rocuronium)
Compared to experimental arm, the active comparator arm received the same procedure except in the analgesia maintenance which was performed through continuous fentanyl infusion. However, during craniotomy surgery, pain may occur in patients in any arms. This was defined as a sudden rise of heart rate and blood pressure higher than 20% from baseline. In that case, a bolus of fentanyl was administered as rescue analgesia.
Dr. Soetomo Hospital, Surabaya, Surabaya
Dr. Soetomo Hospital, Surabaya
UNKNOWN
Kementerian Riset dan Teknologi / Badan Riset dan Inovasi Nasional, Indonesia
OTHER_GOV
Universitas Airlangga
OTHER