Propranolol Adjuvant Treatment of Focal Refractory Epilepsy (PATFRE)

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

December 5, 2024

Primary Completion Date

December 1, 2027

Study Completion Date

December 1, 2028

Conditions
Epilepsy, Drug Resistant
Interventions
DRUG

Propranolol

Oral administration is given solely for the epilepsy seizure event. Dosage: 20mg per dose; The patient's blood pressure and heart rate are monitored after the seizure; if the SBP is above 90 mmHg and the heart rate is above 60 beats per minute, then patients are instructed to take propranolol within 1 hour of a seizure . If the seizure frequency is excessively high, the interval between doses should be no less than 6 hours and the medication should not be administered more than 3 times a day.

All Listed Sponsors
collaborator

Peking University

OTHER

lead

Xuanwu Hospital, Beijing

OTHER