A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

PHASE3RecruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

November 11, 2024

Primary Completion Date

October 31, 2026

Study Completion Date

November 30, 2026

Conditions
Developmental and Epileptic Encephalopathy
Interventions
DRUG

LP352

LP352 will be administered orally or through G-tube/ percutaneous endoscopic gastrostomy (PEG) tube

DRUG

Placebo

Participants will be administered with matching placebo orally or through G-tube/ PEG tube.

Trial Locations (57)

2031

RECRUITING

Prince of Wales Hospital, Randwick

RECRUITING

Sydney Children's Hospital, Randwick

3084

RECRUITING

Austin Hospital, Heidelberg

4006

RECRUITING

Royal Brisbane & Women's Hospital, Herston

4101

RECRUITING

Queensland Children's Hospital, South Brisbane

8041

RECRUITING

Hospital de La Santa Creu i Sant Pau, Barcelona

11000

RECRUITING

University Clinical Center of Serbia - Dr Subotica 6 - PPDS, Belgrade

RECRUITING

Clinic for Neurology and Psychiatry for Children and Youth, Belgrade

13386

RECRUITING

AP-HM- Hôpital de La Timone, Marseille

24105

RECRUITING

Universitätsklinikum Schleswig-Holstein - Campus Kiel, Kiel

28010

RECRUITING

Hospital Universitario Vithas Madrid La Milagrosa, Madrid

28034

RECRUITING

Hospital Ruber Internacional (Grupo Quironsalud), Madrid

29010

RECRUITING

Hospital Regional Universitario de Malaga - Hospital General, Málaga

29016

RECRUITING

Hospital Vithas Malaga, Málaga

30329

COMPLETED

Rare Disease Research, LLC - Atlanta - RDR - PIN, Atlanta

31008

RECRUITING

Hospital Universitario de Navarra, Pamplona

31330

RECRUITING

Centre Hospitalier Universitaire de Toulouse, Toulouse

33606

RECRUITING

University of South Florida - 2 Tampa General Circle, Tampa

33617

RECRUITING

Gesellschaft für Epilepsieforschung e.V., Bielefeld

34000

RECRUITING

University Clinical Center Kragujevac, Kragujevac

35203

RECRUITING

CHU de Rennes - Hôpital Pontchaillou, Rennes

46026

RECRUITING

Hospital Universitari i Politecnic La Fe de Valencia, Valencia

53127

RECRUITING

Universitätsklinikum Bonn, Bonn

59000

RECRUITING

Hôpital Roger Salengro, Lille

60528

RECRUITING

Klinikum der Johann-Wolfgang Goethe-Universitat, Frankfurt am Main

67098

RECRUITING

CHU de Strasbourg - Hôpital de Hautepierre, Strasbourg

69500

RECRUITING

Hospices Civils de Lyon - Hôpital Pierre Wertheimer, Bron

72202

RECRUITING

Arkansas Children's Hospital - PIN, Little Rock

75019

RECRUITING

AP-HP - Hôpital universitaire Robert-Debré, Paris

77030

RECRUITING

The University of Texas Medical School at Houston, Houston

78757

RECRUITING

Child Neurology Consultants of Austin, Austin

88214

RECRUITING

Epilepsie-Zentrum Bodensee, Ravensburg

102627

RECRUITING

Peking University First Hospital - Daxing Campus, Beijing

190133

RECRUITING

Mother and Child Health Care Institute of Serbia Dr Vukan Cupic, Belgrade

94304-1510

RECRUITING

The Stanford Division of Child Neurology, Palo Alto

94143-2350

RECRUITING

UCSF Children's Hospital, San Francisco

80045-7106

RECRUITING

Children's Hospital Colorado., Aurora

32561-4458

RECRUITING

NW FL Clinical Research Group, LLC, Gulf Breeze

33155-3009

RECRUITING

Nicklaus Children's Hospital - PIN, Miami

32806-5411

RECRUITING

Research Institute of Orlando LLC, Orlando

33609-4190

RECRUITING

Pediatric Epilepsy and Neurology Specialists, Tampa

20817-1844

RECRUITING

Mid-Atlantic Epilepsy and Sleep Center, Bethesda

02114

RECRUITING

Massachusetts General Hospital - 175 Cambridge St, Boston

55905-0001

RECRUITING

Mayo Clinic - PIN, Rochester

07039-5817

RECRUITING

Institute of Neurology and Neurosurgery at Saint Barnabas, LLC, Livingston

07960

RECRUITING

Northeast Regional Epilepsy Group - Morristown - 310 Madison Ave, Morristown

97239-3011

RECRUITING

Oregon Health and Science University, Portland

38103-2816

RECRUITING

Le Bonheur Childrens Hospital, Memphis

76104-2710

RECRUITING

Cook Children's Medical Center - Jane and John Justin Neurosciences Center, Fort Worth

98405-4048

RECRUITING

Multicare Health System - Mary Bridge Pediatrics, Tacoma

01454

RECRUITING

Epilepsiezentrum Kleinwachau gemeinnützige Gmbh, Radeberg

LV-1004

RECRUITING

Children's Clinical University Hospital, Riga

3584 CX

RECRUITING

Universitair Medisch Centrum Utrecht - PPDS, Utrecht

08950

RECRUITING

Hospital Sant Joan de Deu - PIN, Espluges de Llobregat

08035

RECRUITING

Hospital Universitario Vall d'Hebron - PPDS, Barcelona

G51 4TF

RECRUITING

Queen Elizabeth University Hospital - PPDS, Glasgow

NE1 4LP

RECRUITING

Royal Victoria Infirmary, Newcastle upon Tyne

Sponsors
All Listed Sponsors
lead

Longboard Pharmaceuticals

INDUSTRY