The Efficacy and Safety of Remimazolam Besylate for Cardiac Anesthesia

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

January 31, 2025

Primary Completion Date

May 31, 2025

Study Completion Date

June 30, 2025

Conditions
Anesthesia
Interventions
DRUG

remimazolam besylate

Patients received an initial dose of remimazolam (0.3mg/kg) for induction and a continuous infusion rate of 1 mg/kg/h for anesthesia maintenance. Sedative was adjusted to maintain a bispectral index (BIS) at 40-60 after induction.

DRUG

propofol

Patients received an initial dose of propofol (1.0 mg/kg) and a continuous infusion rate of 1-1.5 mg/kg/h. Sedative was adjusted to maintain a bispectral index (BIS) at 40-60 after induction.

All Listed Sponsors
lead

Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER